Big Pharma

The Future You Paves the Way to Personalized Health and Wellness for Everyone     Boston, November 2, 2022 ― Do you sleep better if dinner is at 6 p.m. or 8 p.m.? Do you run slower the day after having a glass of wine? How many hours of sleep are optimal for you, personally? All of these answers can be found at your fingertips thanks to AI-enabled devices and wearables, and it’s not as complicated — or as scary — as you might think, explains biotech expert Harry Glorikian.   “I’m looking at technology as being a personalized dashboard...

New bone imaging technique could lead to improved osteoporosis treatment SASKATOON – More than 2.3 million Canadians are affected by osteoporosis, resulting in billions of dollars in economic burden and incalculable suffering. A research team from the College of Medicine at the University of Saskatchewan has developed a new approach to imaging that detects changes in bone tissue far more quickly than bone densitometry scans, the method currently used in health care. While the study was done using a rabbit model, the results could lead to improved drug treatment in humans with osteoporosis. Using the BMIT beamline of the Canadian...

Experts pave the way for safer surgery to address global elective waiting lists   Surgical care experts have today (31 Oct) unveiled two studies in The Lancet that will help to provide safer surgery for thousands of patients around the world – particularly in Low- and Middle-income Countries (LMIC). Researchers found that routinely changing gloves and instruments just before closing wounds could significantly reduce Surgical Site Infection (SSI) – the world’s most common post-operative complication. Secondly, they tested a new toolkit that can make hospitals better prepared for pandemics, heatwaves, winter pressures and natural disasters that could reduce cancellations of...

Understanding oral bacteria to help fight periodontal disease Wilfrid Laurier researchers are exploring how bacteria target weak points in the connective ligaments in your mouth. Using the extremely brilliant light of the Canadian Light Source at the University of Saskatchewan, researchers from Wilfrid Laurier University have advanced our understanding of how a specific group of bacteria in the human mouth contribute to periodontal disease. Dr. Michael Suits and his colleagues were focused on a group of three different bacteria — commonly referred to as the “red complex” — as key contributors to infections and inflammation of the gums and bones...

Serum TDP-43 levels can help to identify common neuropathological changes associated with frontotemporal dementia Frontotemporal dementia (FTD) is one of the most common causes of progressive dementia in working-age people. However, making a diagnosis and a prognosis is often challenging because the frontotemporal dementia spectrum includes several subtypes that differ in terms of symptoms, genetics and neuropathology, i.e., changes in the brain associated with the disease. Typically, proteins accumulating in the brain of patients with FTD and harming their neurons are either TDP-43 or tau proteins. Understanding the neuropathological changes in patients already at the diagnostic stage would be particularly...